Three Major Model Releases Expected in April as GPT-5.4 Scores 95% on the USA Mathematical Olympiad
Three major model releases expected in April
GPT-5.5, Claude 5 Mythos, and DeepSeek-V4 are all expected to drop in April. Commentators warn this could make frontier intelligence too expensive for most users as massive training runs become table stakes, putting pressure on rate limits and pricing.
In OpenAI's Parameter Golf competition, a challenge to train the best language model that fits in a 16MB artifact on 8xH100s, the best claimed result is now 42.7x better than the baseline.
Last year, models scored below 5% on USAMO 2025, the USA Mathematical Olympiad. GPT-5.4 just scored 95% on the 2026 exam.
AI in biology
Anthropic is testing Claude Operon, a desktop mode for biology, from phylogenetic trees to CRISPR knockout screens. Phylogenetic trees show evolutionary relationships between species, and CRISPR knockout screens systematically disable genes to see what happens.
Researchers have demonstrated the first integrated framework for how epigenetic regulation controls aging. Epigenetic regulation refers to changes in gene activity that do not involve altering the DNA sequence itself.
Northwestern scientists created HOBIT, a "living pharmacy" implant that kept engineered cells alive for a month inside rats while dosing three drugs at once, including a GLP-1 medication.
Neko Health, founded by Spotify's Daniel Ek, plans to open its first US body-scan clinic in New York this spring.
The man who developed a custom mRNA immunotherapy for his dog's cancer using Gemini, Grok, and ChatGPT is now starting a company to end cancer for dogs.
Robotics
Northwestern researchers introduced autonomous modular legs, single-degree-of-freedom links that learn complex behaviors and snap together to form acrobatic multilegged machines at the meter scale.
China's Agibot is about to ship 10,000 humanoid robots, double its milestone from just one quarter ago.
Cyan Robotics unveiled "Amoo," an under-80-cm companion robot with sub-30-ms synchronized eye and body language.
Two US senators plan to introduce the American Security Robotics Act to ban government use of Chinese robots.
The Tesla Model Y has emerged as the world's best-selling car for the third consecutive year.
Infrastructure
Sam Altman shared that the first steel beams went up at the Michigan Stargate site.
South Korea now mandates solar panels for public parking lots with 80 or more spaces.
The DOE's reactor pilot program could see three to four microreactors reach criticality by July 4. Criticality means the reactor sustains a controlled nuclear chain reaction.
The Space Biostasis Coalition has launched to mobilize $1 billion into engineering human cryosleep for space travel.
NASA announced it will send Space Reactor-1 Freedom, the first nuclear-powered interplanetary spacecraft, to Mars before the end of 2028, carrying a fleet of tiny "Skyfall" helicopters.
IBM and collaborators demonstrated that a superconducting quantum processor can produce meaningful comparisons with neutron-scattering measurements on up to 50 qubits, a milestone for material simulation before full error correction is available.
Security and deployment
Anthropic researcher Nicolas Carlini demonstrated autonomous 0-day discovery on stage. A 0-day is a previously unknown security vulnerability.
At Google, a principal engineer reports that PMs are running circles around SWEs with vibe coding tools.
Linux kernel maintainer Greg Kroah-Hartman says AI-driven security reporting has "really jumped" across all open source projects in the past month.
Claude's paid subscriptions have more than doubled this year.
Other news
Chess grandmasters, all training on the same AI moves, are now winning by playing suboptimal moves their opponents have not practiced.
Research finds that large language models elevate expert consensus and moderate views, in contrast to the polarization of social platforms.
Samsung's Family Hub refrigerators have started serving full-screen ads on their 32-inch doors.
That's today. More tomorrow.
Matthew Ortiz
CEO, OTZ Group